Hepatitis B Virus Infection and Primary Hepatocellular Carcinoma 2 3

Autor:	Chao H. Chan, Edward Tabor, Anne C. Bayley, Peter P. Anthony, Lewellys F. Barker, Charles L. Vogel, Robert J. Gerety
Rok vydání:	1977
Předmět:	Hepatitis Hepatitis B virus Cancer Research HBsAg biology business.industry virus diseases Hepatitis B medicine.disease medicine.disease_cause Virology digestive system diseases Oncology Antigen HBeAg Hepatocellular carcinoma parasitic diseases biology.protein medicine Antibody business
Zdroj:	JNCI: Journal of the National Cancer Institute. 58:1197-1200
ISSN:	1460-2105 0027-8874
DOI:	10.1093/jnci/58.5.1197
Popis:	Ninety-three patients with biopsy-proven primary hepatocellular carcinoma (PHC) from Uganda, Zambia, and the United States were examined for serologic evidence of hepatitis B virus (HBV) infection. Patients were tested for hepatitis B surface antigen (HBsAg) and its antibody (anti-HBs), antibody to the hepatitis B core antigen (anti-HBc), hepatitis B e antigen (HBeAg), and its antibody (anti-HBe). Active HBV infection, as indicated by positive tests for HBsAg (with or without anti-HBs) and anti-HBc (without anti-HBs), was present in 62% of PHC patients (58 of 93), in contrast with 10% of African controls (9 of 90), and less than 1% of most United States adult populations reported in the literature. The presence of HBeAg or anti-HBe was rare among PHC patients and controls.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::453ec80a5e140d797f0895c5f35936ac https://doi.org/10.1093/jnci/58.5.1197 Zobrazit plný text záznamu