Adaptation mechanisms of the immune reaction in rats under the influence of moderately low temperatures in combination with low frequency electromagnetic radiation
| Autor: | Kseniia Zub, Olena Litovchenko, M. M. Mishyna |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0303 health sciences
biology Chemistry 030302 biochemistry & molecular biology Biophysics Medicine (miscellaneous) 030209 endocrinology & metabolism Spleen Low frequency Electromagnetic radiation Complement system 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Immune system medicine biology.protein Adaptation Immune reaction Antibody |
| Zdroj: | Problems of Cryobiology and Cryomedicine. 30:256-269 |
| ISSN: | 2518-7376 2307-6143 |
| Popis: | The immune system maintains a balance between the body's vital functions and influence of exogenous factors. Immune mechanisms are activated by the innate and adaptive response that allows the body to adapt to new living conditions, characterized by the simultaneous action of various factors. An experimental research in rats (for 30 days) studied the effect of moderately low temperatures (2-6°C), or in combination with electromagnetic radiation (70 kHz, 600 V/m) on the immune system to establish the features of adaptive-immunological responses of an organism. It was found that the effect of moderately low temperatures compared with the combined influence of electromagnetic radiation had a more pronounced effect, which was manifested by activation of the complement system (increased C4 and C5), increased concentrations of immunoglobulins (IgM, IgG) and enhanced functional activity of spleen (increased lymphoid follicles and their reactive centers). However, under the combined influence of the factors, the changes were less pronounced and modified (decrease in C4 content), that indicated the development of negative cross-adaptation in the immune system of animals. Probl Cryobiol Cryomed 2020; 30(3): 256–269 |
| Databáze: | OpenAIRE |
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