ChemInform Abstract: An Allylic Isoprenoid C5 Nucleophile for the Synthesis of Forskolin

Autor:	Peter Welzel, Stefan Hamm, Dirk Behnke, Lothar Hennig
Rok vydání:	2010
Předmět:	Labdane chemistry.chemical_compound Allylic rearrangement Addition reaction Forskolin chemistry Nucleophile Stereochemistry Yield (chemistry) General Medicine Stannane Derivative (chemistry)
Zdroj:	ChemInform. 29
ISSN:	1522-2667 0931-7597
Popis:	InCl 3 -mediated coupling of δ-alkoxy allylic stannane 9b with aldehydes has been shown to give the α-coupling products in high yield, probably via two S e ′ processes. Most specifically, drimenal ( rac- 1 ) has been converted into labdane derivative 17 which is considered to be an important intermediate on the way to forskolin.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::451d8b31b6594ebf11dc5a153650de0a https://doi.org/10.1002/chin.199802053 Zobrazit plný text záznamu Plný text