Postoperative analgesic efficacy of caudal dexamethasone added to bupivacaine vs bupivacaine alone for pediatric elective infra-umbilical surgery at (Tikur Anbesa Specialized Hospital), Ethiopia: Prospective cohort study
| Autor: | Zemedu Aweke, Mulualem sitot, Amanu Gashaw, Getahun Dendir, Bahailu Balcha |
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| Rok vydání: | 2020 |
| Předmět: |
Bupivacaine
α2 agonists Umbilical surgery business.industry Postoperative pain Analgesic 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Anesthesia Mann–Whitney U test Medicine 030211 gastroenterology & hepatology Surgery business Prospective cohort study Dexamethasone medicine.drug |
| Zdroj: | International Journal of Surgery Open. 24:170-176 |
| ISSN: | 2405-8572 |
| DOI: | 10.1016/j.ijso.2020.05.003 |
| Popis: | Background Caudal block is the most preferred technique of postoperative analgesia in pediatrics, despite its limited duration of action. Many additives are used to improve the efficacy of caudal blocks, such as opioids or α2 agonists. Recently, there has been increased use of caudal dexamethasone as postoperative analgesia. Objective To assess the efficacy of adding caudal dexamethasone on bupivacaine for postoperative analgesia in pediatric infra-umbilical surgery. Method A prospective cohort study design was employed for two equal groups of 30 children aged 1–14 years scheduled for infra-umbilical surgery under caudal bupivacaine; those exposed to dexamethasone (BD) were considered to be the exposed group and those exposed to bupivacaine alone (B) were the non-exposed group. Pain severity, first analgesia request time as well as analgesic consumption were assessed using Mann-Whitney U test for 24 h. Chi-square test was used to analyze the homogenous categorical independent variables between these two groups and a p-value less than 0.05 was considered to be statistically significant. Result The dexamethasone with bupivacaine group had significant prolonged postoperative analgesia with a median of 915 (650–1,440) minutes compared with 433 (328–555) minutes in the bupivacaine-alone group (p Conclusion Dexamethasone with bupivacaine decreases postoperative pain severity and total analgesic consumption and prolongs the duration of analgesia. Therefore, we recommend the use of caudal dexamethasone with bupivacaine as an effective option for postoperative analgesia. |
| Databáze: | OpenAIRE |
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