Effects of strong cytochrome P450 (CYP)3A4 inducers/inhibitors on the pharmacokinetic (PK) profile of anamorelin in healthy volunteers
Autor: | Alberto Bernareggi, Elizabeth Manning Duus, Mark A. Matson |
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Rok vydání: | 2018 |
Předmět: |
Agonist
Cancer Research biology Anamorelin medicine.drug_class business.industry digestive oral and skin physiology Cytochrome P450 Anorexia Pharmacology medicine.disease Cachexia Oncology Pharmacokinetics biology.protein medicine Ghrelin medicine.symptom Receptor business hormones hormone substitutes and hormone antagonists |
Zdroj: | Journal of Clinical Oncology. 36:e22180-e22180 |
ISSN: | 1527-7755 0732-183X |
DOI: | 10.1200/jco.2018.36.15_suppl.e22180 |
Popis: | e22180Background: Anamorelin is an oral selective ghrelin receptor agonist in development that showed benefits for patients with advanced non-small cell lung cancer and anorexia/cachexia (ROMANA st... |
Databáze: | OpenAIRE |
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