A new surface modification technique of platinum coils by ion implantation and protein coating: Use in intravascular treatment of brain aneurysms

Autor:	Huy M. Do, Toshiaki Abe, Yuichi Murayama, Tarik F. Massoud, Fernando Vinuela, Guido Guglielmi, Masami Kamio, M. Iwaki, Yoshiaki Suzuki
Rok vydání:	1997
Předmět:	Nuclear and High Energy Physics Materials science Thrombogenicity Cell migration Adhesion engineering.material Ion implantation Coating engineering Surface modification Cell adhesion Wound healing Instrumentation Biomedical engineering
Zdroj:	Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. :1015-1018
ISSN:	0168-583X
DOI:	10.1016/s0168-583x(97)00080-3
Popis:	Ion implantation and protein-coatings were utilized to alter the surface properties (thrombogenicity, endothelial cellular migration and adhesion) of microcoils (GDCs) for intravascular treatment of brain aneurysms. These modified coils were compared with standard GDCs in the treatment of experimental swine aneurysms. Improved cellular adhesion and proliferation was observed with use of the modified coils. The results of this preliminary investigation indicate that future application of this technology may provide early wound healing at the necks of embolized wide-necked brain aneurysms.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::44e616555ebcb4d79866b8e22f1100c6 https://doi.org/10.1016/s0168-583x(97)00080-3 Zobrazit plný text záznamu Full Text from ScienceDirect