Rates of autism and potential risk factors in children with congenital heart defects

Autor: Elaine H. Zackai, Donna M. McDonald-McGinn, Robert R. Clancy, Cynthia Solot, Thomas B. Flynn, Jesse L Chittams, Therese Sammarco, Jessica L Bean Jaworski, Judy Bernbaum, J. William Gaynor, Nancy Burnham, Marsha Gerdes
Rok vydání: 2017
Předmět:
Zdroj: Congenital Heart Disease. 12:421-429
ISSN: 1747-079X
Popis: Objective Atypical development, behavioral difficulties, and academic underachievement are common morbidities in children with a history of congenital heart defects and impact quality of life. Language and social-cognitive deficits have been described, which are associated with autism spectrum disorders. The current study aimed to assess the rates of autism spectrum disorders in a large sample of children with a history of congenital heart defects and to assess medical, behavioral, and individual factors that may be associated with the risk of autism spectrum disorders. Design Participants included 195 children with a history of congenital heart defects, who are followed in a large-scale longitudinal study. Measures included behavioral data from 4-year-old neurodevelopmental evaluations and parent-report data from a later annual follow-up. Results Using established cutoffs on an autism spectrum disorder screener, children with congenital heart defects showed higher rates of “possible” autism spectrum disorders than national rates, (Chi-square Test of Equal Proportions), all Ps
Databáze: OpenAIRE