Guided tissue regeneration using a polylactic acid barrier. Part I: Environmental effects on bacterial colonization

Autor: Benjamin Ehmke, Helge Karch, A. Hommens, Stefan G. Rüdiger, Thomas Frank Flemmig
Rok vydání: 2003
Předmět:
Zdroj: Journal of Clinical Periodontology. 30:19-25
ISSN: 0303-6979
DOI: 10.1034/j.1600-051x.2003.300104.x
Popis: Objectives: The purpose of this study was to assess the dynamics of bacterial colonization in intra-osseous defects following guided tissue regeneration (GTR) therapy using a resorbable barrier. Patients and methods: In each of 30 patients, one intra-osseous defect was treated with GTR using a polylactic acid membrane (Guidor®). Plaque samples were taken from the defect site, other teeth and mucous membranes following initial therapy (baseline), and at 3, 6 and 12 months after periodontal surgery. Additionally, samples were taken from the defect sites at 1, 2 and 4 weeks. Actinobacillus actinomycetemcomitans (A.a.), Porphyromonas gingivalis (P.g.), and Bacteroides forsythus (B.f.) were detected by polymerase chain reaction (PCR). Supportive periodontal therapy was performed at 3-month intervals. Results: In the 29 patients completing the study, the assessed microflora was detected in 3 (A.a.), 13 (P.g.) and 14 (B.f.) defect sites at baseline, in 2 (A.a.), 2 (P.g.) and 2 (B.f.) following surgical debridement, and in 6 (A.a.), 10 (P.g.) and 22 (B.f.) at 12 months. Defect site colonization following GTR therapy was significantly correlated with presurgical colonization at other assessed teeth (A.a. and P.g.: tau = 0.45 and 0.66, respectively; P
Databáze: OpenAIRE
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