Physical methods for measurement of the HLB of ether and ester non-ionic surface-active agents: H-NMR and dielectric constant

Autor:	M. Seiller, A. Rabaron, G. Cavé, Francis Puisieux
Rok vydání:	1993
Předmět:	chemistry.chemical_compound Hydrophilic-lipophilic balance Chromatography chemistry Non ionic Polarity (physics) Proton NMR Pharmaceutical Science Physical chemistry Molecule Ether Dielectric Surface-active agents
Zdroj:	International Journal of Pharmaceutics. 99:29-36
ISSN:	0378-5173
DOI:	10.1016/0378-5173(93)90319-b
Popis:	After a short review of the different physical methods of determination of the HLB (lipophilic/hydrophilic balance) value of surface-active agents, two techniques were investigated and experiments were performed on a large number of commercial surface-active agents: H-NMR which computes HLB with the help of the integration of the H-signals from the lipophilic and hydrophilic parts of the molecule and by dielectric constant measurement which computes the HLB from knowledge of the polarity of molecules under the influence of an electrical field. The results are described and discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::44cd13a85f90ac587b1b4906dd2b2540 https://doi.org/10.1016/0378-5173(93)90319-b Zobrazit plný text záznamu