Regulation of hyaluronan synthesis and the interaction of hyaluronan with cells

Autor: Tomas Asplund, Håkan Pertoft, Masanobu Suzuki, Priit Teder, Vasilios Papanikolaou, Dionisios Vrochides, Paraskevi Heldin
Rok vydání: 1995
Předmět:
Zdroj: Acta Orthopaedica Scandinavica. 66:160-162
ISSN: 0001-6470
Popis: Hyaluronan is a high molecular weight polysaccharide ubiquitously found in the extracellular matrix. It acts as a lubricant in joints and tissues and provides stability and elasticity to the extracellular matrix. In addition, hyaluronan is directly or indirectly implicated in cell growth, angiogenesis, differentiation and malignant tumor invasion (for a review see Laurent and Fraser 1992, Sherman et al. 1994). This review focuses on the regulation of the biosynthesis of hyaluronan and the formation and structure of the pericellular coat around hyaluronan producing cells.
Databáze: OpenAIRE