Regulation of hyaluronan synthesis and the interaction of hyaluronan with cells
Autor: | Tomas Asplund, Håkan Pertoft, Masanobu Suzuki, Priit Teder, Vasilios Papanikolaou, Dionisios Vrochides, Paraskevi Heldin |
---|---|
Rok vydání: | 1995 |
Předmět: |
chemistry.chemical_classification
integumentary system Angiogenesis business.industry Polysaccharide Cell biology carbohydrates (lipids) Extracellular matrix chemistry.chemical_compound chemistry Biosynthesis Biochemistry Medicine Orthopedics and Sports Medicine Surgery Hyaluronan synthesis business |
Zdroj: | Acta Orthopaedica Scandinavica. 66:160-162 |
ISSN: | 0001-6470 |
Popis: | Hyaluronan is a high molecular weight polysaccharide ubiquitously found in the extracellular matrix. It acts as a lubricant in joints and tissues and provides stability and elasticity to the extracellular matrix. In addition, hyaluronan is directly or indirectly implicated in cell growth, angiogenesis, differentiation and malignant tumor invasion (for a review see Laurent and Fraser 1992, Sherman et al. 1994). This review focuses on the regulation of the biosynthesis of hyaluronan and the formation and structure of the pericellular coat around hyaluronan producing cells. |
Databáze: | OpenAIRE |
Externí odkaz: |