Association between myocardial mechanical dispersion and ventricular arrhythmogenicity in chagas cardiomyopathy

Autor: Thor Edvardsen, Henrique Silveira Costa, L. G. Klaboe, Maria do Carmo Pereira Nunes, Manoel Otávio da Costa Rocha, G. M. M. Paixao, O. R. Santos Junior, A. C. A. Azevedo, M. V. L. Barros
Rok vydání: 2021
Předmět:
Zdroj: The International Journal of Cardiovascular Imaging. 37:2727-2734
ISSN: 1573-0743
1569-5794
DOI: 10.1007/s10554-021-02246-8
Popis: Chagas disease is a major health concern in Latin America. Ventricular arrhythmia (VA) is a hallmark of Chagas cardiomyopathy (CCM), associated with worse prognosis. The present study aimed to verify the association between myocardial mechanical dispersion (MD) and ventricular arrhythmogenicity in CCM. In a cross-sectional study, 77 patients (55.8 ± 10.4 years) with CCM were evaluated. Global longitudinal strain (GLS) and MD were assessed by echocardiography, derived from the speckle tracking technique. Myocardial MD was measured from the onset of the Q/R wave on electrocardiogram to the peak longitudinal strain in 16 segments of the left ventricle. Frequency and complexity of ventricular extrasystoles (VES) were assessed by dynamic electrocardiography. The density and complexity of VES and the presence of non-sustained ventricular tachycardias (NSVTs) increase as MD increases. In logistic regression, MD was the only variable associated with the presence of paired VES and ventricular bigeminy. In addition, both MD and GLS were associated with the presence of NSVT (both, p
Databáze: OpenAIRE
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