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People living-with HIV (PLHIV) presented less richness and diversity in the intestinal microbiota than non-infected individuals. Immunopathogenesis of HIV-1 infection has been extensively studied, however the influence of microbiota in those parameters that are key in the pathogenesis are less well characterized. The aim of the current study was to characterize the faecal microbiota composition in a cohort of PLHIV and its relationship with the clinical, metabolic, nutritional, inflammation, bacterial translocation and immunological markers. Baseline faecal samples from seventy-six HIV infected individuals with undetectable viral load (uVL) from a prospective, randomized feeding trial (NCT03846206) were collected and processed. The gut microbiota was determined by sequencing the V3-V4 region of the 16S rRNA gene. After analysing alpha diversity, women presented less diversity (Fisher alpha, P |
