Effects of Dehydroepiandrosterone Sulfate on Aldosterone Levels on Exposure to Cold

Autor: E. T. Obut, T. A. Erdynieva, T. Yu. Dementieva, M. V. Ovsyukova, T. A. Obut, S. K. Saryg
Rok vydání: 2012
Předmět:
Zdroj: Neuroscience and Behavioral Physiology. 42:651-653
ISSN: 1573-899X
0097-0549
Popis: Treatment of rats with dehydroepiandrosterone sulfate (DEAS) at doses of 1, 5, and 30 mg/kg were found to block cold-induced increases in blood aldosterone levels, though the effect was not dose-dependent in conditions of repeated cold exposure. This effect of DEAS involved μ opioid receptors. The blocking effect of DEAS (30 mg/kg) was also seen with single episodes of cold exposure, but without the involvement of μ opioid receptors.
Databáze: OpenAIRE