Osteoarticular Amilodosis in the Hip Associated with Long-term Hemodialysis: A Case Report

Autor: Masashi Kataoka, Hiroshi Tsumura, Shinsaku Ogimoto, Mitsuhiro Takasita, Hirofumi Matsumoto, Nobuhiro Kaku
Rok vydání: 2001
Předmět:
Zdroj: Orthopedics & Traumatology. 50:249-254
ISSN: 1349-4333
0037-1033
DOI: 10.5035/nishiseisai.50.249
Popis: A forty-five-year-old female who had been on hemodialysis for twenty six years developed extensive bone cyst in the femoral head. The cystic lesion showed low-signal intensity on T1-weighted images of magnetic resonance imaging. On T2-weighted images, it showed iso-signal intensity. She experienced hip pain and the cystic area in the plain radiograph covered 37.5% of the femoral head using the lateral head index. We therefore performed hip arthroplasty with bipolar endoprosthesis. At operation, we found a change in the color of the articular cartilage, synovium proliferation and granulation tissue in the joint space. Histological examination using dylon staining showed amiloid deposition in the cartilage, synovial membrane, granulation tissue and bone specimens. In addition, the existance of many inflammatory cells in the synovial membrane and some giant cells like osteoclast contacting with the bone trabecular around amiloid was demonstrated pathologically.
Databáze: OpenAIRE