Synthesis of 2H,3-4-Dihydro-1,2-benzoselenazin-3-one and derivatives : A new heterocyclic ring system

Autor:	Léon Christiaens, Norbert Dereu, Michel Evers, Pierre V. Jacquemin, Marcel Renson
Rok vydání:	1992
Předmět:	Bicyclic molecule medicine.drug_class Stereochemistry Ebselen Organic Chemistry Carboxamide Glutathione Ring (chemistry) Biochemistry chemistry.chemical_compound chemistry Drug Discovery medicine Spectral data
Zdroj:	Tetrahedron Letters. 33:3863-3866
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)74805-2
Popis:	The synthesis of 2H-3,4-dihydro-1,2-benzoselenazin-3-ones which are six-membered homologues of Ebselen is described in order to evaluate their glutathione peroxidase-like activity. Spectral data of these new heterocycles are given.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4473eda2a60ff9aafa17249c59194e21 https://doi.org/10.1016/s0040-4039(00)74805-2 Zobrazit plný text záznamu