Synthesis and antitumor activity of pyridoxine monoalkenyl derivatives

Autor:	T. T. Nguyen, Olga A. Lodochnikova, Mikhail V. Pugachev, Yu. G. Shtyrlin, Alfiya G. Iksanova, Roman S. Pavelyev
Rok vydání:	2016
Předmět:	Antitumor activity 010405 organic chemistry Chemistry General Chemistry 010402 general chemistry Pyridoxine 01 natural sciences Chloride In vitro 0104 chemical sciences Wittig reaction medicine Organic chemistry Cytotoxicity medicine.drug
Zdroj:	Russian Chemical Bulletin. 65:532-536
ISSN:	1573-9171 1066-5285
Popis:	A convenient method for the synthesis of pyridoxine alkenyl derivatives by the Wittig reaction of [(2,8-dimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methyl]triphenylphosphonium chloride with aldehydes was suggested. Some of the compounds obtained exhibit antitumor activity in vitro.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::446dba5c53624def176aa2a77d699d2f https://doi.org/10.1007/s11172-016-1333-z Zobrazit plný text záznamu Full text from SpringerLink