Characteristics of cytotoxic T lymphocytes eluted from allogeneic target cells

Autor: Egorov Sg, Brondz Bd
Rok vydání: 1977
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 83:57-60
ISSN: 1573-8221
0007-4888
Popis: The increase in the specific cytotoxic effect of immune lymphocytes after their adsorption on the corresponding target cells (TC) and subsequent elution with pronase is due, not to increased cytotoxic activity of individual cells, but to a quantitative increase in the proportion of effector T cells in the population. The eluted and original immune lymphocytes are indistinguishable in the kinetics of their adsorption on TC. The fraction of eluted lymphocytes contains twice as many T cells and four to five times as many cells synthesizing DNA, on account of an increase in the percentage of medium-sized and large lymphocytes.
Databáze: OpenAIRE