Adiponectin negatively correlates with alcoholic and non-alcoholic liver dysfunction: Health check-up study of Japanese men

Autor:	Yuji Matsuzawa, Norihiro Chatani, Mina Hamano, Kenji Watabe, Akira Yamada, Toshimitsu Hamasaki, Shusaku Tsutsui, Yoshihiro Kamada, Yoshifumi Tsukamoto, Kazuo Kinoshita, Takashi Fujimoto, Kunimaro Furuta, Norio Hayashi, Hisao Ezaki, Tetsuo Takehara, Shinichi Kiso, Osamu Kishida, Mayumi Egawa, Takayo Takemura, Miyuki Umeda, Yuichi Yoshida, Takashi Kizu, Aiko Furubayashi
Rok vydání:	2012
Předmět:	medicine.medical_specialty Waist Hepatology Adiponectin business.industry Fatty liver medicine.disease Obesity Infectious Diseases Endocrinology Insulin resistance Internal medicine medicine Liver dysfunction business Alcohol consumption Homeostasis
Zdroj:	Hepatology Research. 43:238-248
ISSN:	1386-6346
Popis:	Aim: Central obesity, insulin resistance and alcohol consumption are thought to be major risk factors for fatty liver formation. Adiponectin (APN) prevents fatty liver formation, and its serum levels are lower in subjects with central obesity and/or insulin resistance. The aim of this study was to explore the association among serum APN levels, central obesity, insulin resistance and liver dysfunction with or without fatty liver classified by alcohol consumption in healthy subjects. Methods: A total of 5588 Japanese male subjects who underwent a health check-up were classified into three groups according to alcohol consumption: non- or light drinkers (15 g/day ≥ ethanol); mild drinkers (15 g/day
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::441fd68c9ffbc678ebc6dd235bb47e13 https://doi.org/10.1111/j.1872-034x.2012.01066.x Zobrazit plný text záznamu Plný text