Association Analysis Between Variants in Bovine Progesterone Receptor Gene and Superovulation Traits in Chinese Holstein Cows

Autor:	Liguo Yang, Ke-Qiong Tang, Wu-Cai Yang, SJ Li
Rok vydání:	2011
Předmět:	medicine.medical_specialty Single-nucleotide polymorphism Biology Endocrinology Polymorphism (computer science) Internal medicine Progesterone receptor Genetic variation Genotype medicine Animal Science and Zoology Gene polymorphism Gene Biotechnology Genetic association
Zdroj:	Reproduction in Domestic Animals. 46:1029-1034
ISSN:	0936-6768
Popis:	The objective of this study was to identify a predictor to forecast superovulation response on the basis of associations between superovulation performance and gene polymorphism. The PCR-RFLP method was applied to detect two reported single nucleotide polymorphisms (SNPs) of G59752C and T81637C (rs41614030) located in introns 3 and 4 of the bovine progesterone receptor (PGR) gene in 171 Chinese Holstein cows treated for superovulation and evaluate its associations with superovulation traits. In polymorphic locus 81637, all cows without superovulation response were g.81637TC and g.81637TT genotypes. Association analysis showed that these two SNPs had significant effects on the total number of ova (TNO) (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4410ecf7c12a4c44945f39303b2b23be https://doi.org/10.1111/j.1439-0531.2011.01780.x Zobrazit plný text záznamu Plný text