| Popis: |
Background: Prior small scale studies have reported similar outcomes of left atrial appendage occlusion among diabetics and non-diabetics. Objectives: Using a large nationally representative database, we aimed at examining the impact of diabetes mellitus on outcomes among patients undergoing left atrial appendage occlusion with Watchman device. Methods: We queried the Nationwide Readmission Database to identify left atrial appendage occlusion procedures performed from 2016 to 2017. Multivariable logistic and linear regression models were used to identify the outcomes we sought to explore. The primary outcome of interest was in-patient mortality. Results - Of the 32,679 patients who underwent LAAO during the study period, 11219 (34.3%) had a diagnosis of diabetes mellitus. Comorbidities such as hypertension, COPD, valvular heart disease, heart failure and end stage renal disease were significantly more prevalent among the diabetic group. There was no significant difference in the primary outcome of in-hospital mortality between the 2 groups (adjusted odds ratio, 0.67; 95% CI, 0.32-1.39). There was increased risk of post procedural pericardial effusion/tamponade among the diabetics (adjusted odds ratio, 0.58; 95% CI, 0.38-0.89). The commonest causes of 30 day readmission were similar in both groups. Conclusion: There was no significant difference in the primary outcome among diabetics versus non diabetics undergoing left atrial appendage occlusion with Watchman device. |
