Overexpression of Class I MHC in Murine Trophoblast and Increased Rates of Spontaneous Abortion
| Autor: | Farideh Hooshmand, Joseph R. Voland, Christopher Becker |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Fetus
animal diseases Trophoblast chemical and pharmacologic phenomena biochemical phenomena metabolism and nutrition Biology Major histocompatibility complex Histocompatibility Transplantation medicine.anatomical_structure Immune system Antigen Placenta embryonic structures Immunology medicine biology.protein bacteria |
| Zdroj: | Immunobiology of Reproduction ISBN: 9781461384243 |
| DOI: | 10.1007/978-1-4613-8422-9_15 |
| Popis: | The ability of the placenta to avoid rejection by the maternal immune system has remained a fascinating paradox for the transplantation immunologist. The placenta contains tissue-specific fetal antigens and paternally derived histocompatibility antigens that are potentially antigenic for the maternal immune system. Nevertheless, during the course of a normal pregnancy, deleterious maternal immune responses are not generated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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