Complex flow patterns in a real-size intracranial aneurysm phantom: phase contrast MRI compared with particle image velocimetry and computational fluid dynamics
| Autor: | Christian Poelma, Aart J. Nederveen, E. VanBavel, Mcm Marcel Rutten, J.J. Schneiders, Annetje Guédon, van P Ooij, Henk A. Marquering, Charles B. L. M. Majoie |
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| Rok vydání: | 2011 |
| Předmět: |
Materials science
business.industry media_common.quotation_subject Physics::Medical Physics Resolution (electron density) Pulsatile flow Solenoid Computational fluid dynamics computer.software_genre Imaging phantom Physics::Fluid Dynamics Nuclear magnetic resonance Particle image velocimetry Voxel Molecular Medicine Contrast (vision) Radiology Nuclear Medicine and imaging business computer Spectroscopy media_common |
| Zdroj: | NMR in Biomedicine. 25:14-26 |
| ISSN: | 0952-3480 |
| Popis: | The aim of this study was to validate the flow patterns measured by high-resolution, time-resolved, three-dimensional phase contrast MRI in a real-size intracranial aneurysm phantom. Retrospectively gated three-dimensional phase contrast MRI was performed in an intracranial aneurysm phantom at a resolution of 0.2 × 0.2 × 0.3 mm(3) in a solenoid rat coil. Both steady and pulsatile flows were applied. The phase contrast MRI measurements were compared with particle image velocimetry measurements and computational fluid dynamics simulations. A quantitative comparison was performed by calculating the differences between the magnitude of the velocity vectors and angles between the velocity vectors in corresponding voxels. Qualitative analysis of the results was executed by visual inspection and comparison of the flow patterns. The root-mean-square errors of the velocity magnitude in the comparison between phase contrast MRI and computational fluid dynamics were 5% and 4% of the maximum phase contrast MRI velocity, and the medians of the angle distribution between corresponding velocity vectors were 16° and 14° for the steady and pulsatile measurements, respectively. In the phase contrast MRI and particle image velocimetry comparison, the root-mean-square errors were 12% and 10% of the maximum phase contrast MRI velocity, and the medians of the angle distribution between corresponding velocity vectors were 19° and 15° for the steady and pulsatile measurements, respectively. Good agreement was found in the qualitative comparison of flow patterns between the phase contrast MRI measurements and both particle image velocimetry measurements and computational fluid dynamics simulations. High-resolution, time-resolved, three-dimensional phase contrast MRI can accurately measure complex flow patterns in an intracranial aneurysm phantom. |
| Databáze: | OpenAIRE |
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