Synthesis and antifungal activity of novel aza-d--homosteroids, hydroisoquinolines, pyridines and dihydropyridines

Autor:	G. L. Patrick, O. S. Kinsman
Rok vydání:	1996
Předmět:	Pharmacology Antifungal Broad spectrum Strain (chemistry) In vivo Stereochemistry medicine.drug_class Chemistry Organic Chemistry Drug Discovery Homosteroids medicine General Medicine
Zdroj:	European Journal of Medicinal Chemistry. 31:615-624
ISSN:	0223-5234
DOI:	10.1016/0223-5234(96)89557-2
Popis:	Summary A series of novel aza- d --homosteroids and their hydroisoquinoline precursors were synthesized and tested for antifungal activity against a variety of a strain strains and also s species. A species. A number of 4-substituted pyridines and tetrahydropyridines were also tested. Several compounds showed a broad spectrum of modest antifungal activity and three structures were investigated further for fungicidal and in vivo activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::43e48a66d408c398db2336e142d79c9f https://doi.org/10.1016/0223-5234(96)89557-2 Zobrazit plný text záznamu Full Text from ScienceDirect