INCREASE IN THE URINARY β2-MICROGLOBULIN AFTER HARD LOADING
Autor: | Masana Ogata, Eiji Yunoki, Junko Mizugaki |
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Rok vydání: | 1978 |
Předmět: |
medicine.medical_specialty
Creatinine Chromatography Chemistry Beta-2 microglobulin Health Toxicology and Mutagenesis Urinary system Public Health Environmental and Occupational Health Albumin Radioimmunoassay Urine Excretion chemistry.chemical_compound Endocrinology Sephadex Internal medicine medicine |
Zdroj: | INDUSTRIAL HEALTH. 16:103-109 |
ISSN: | 1880-8026 0019-8366 |
DOI: | 10.2486/indhealth.16.103 |
Popis: | In order to study the factors which have influenced to β2-microglobulin levels in urine, the effect of hard loading on the concentration of urinary β2-microglobulin was studied.Increase in both actual and corrected β2-microglobulin concentration and slight increase in albumin was observed with volunteers in the urine after marathon running.Maximum excretion of urinary β2-microglobulin was observed 30min after cession of exercise.And increase in actual and corrected β2-microglobulin concentration, and the ratio of β2-microglobulin to creatinine in urine of volunteers loaded 210 steps/min for 1 hour were recognized 30 min after cession of exercise by training machine. Similar result of urinary excretion to β2-microglobulin was obtained with those of creatinine.Concentration of β2-microglobulin in serum had a tendency to increase, but concentration of creatinine in serum was not increased.Results of Sephadex G-100 gel filtrations indicated that urinary β2-microglobulin after exercise, which measured by radioimmunoassay, was contained in the filtrated fraction having molecular weight of approximately 11, 800, suggesting that similar substance to HL-A did not excreted in urine after hard loading. |
Databáze: | OpenAIRE |
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