Application of organolithium and related reagents in synthesis, Part XII. Synthesis of phenyl- and pyridylpyridopyridazinones and their derivatives

Autor:	K. Czech, Jan Epsztajn, J. Z. Brzezinski
Rok vydání:	1993
Předmět:	chemistry.chemical_classification chemistry.chemical_compound chemistry Reagent Hydrazine Organic chemistry General Chemistry Alkylation Hydrate Alkyl
Zdroj:	Monatshefte für Chemie Chemical Monthly. 124:549-558
ISSN:	1434-4475 0026-9247
DOI:	10.1007/bf00819523
Popis:	The preparation of the pyridazinones10a,10b,11a,11b, and12a,12b from the ketoamides7,8, and9 and hydrazine hydrate is described. It was found that from ketoamides8b and9b in addition to the expected pyridopyridazinones11b and12b also aminopyridopyridazines14 and15 were formed and that ketoamide7b gave exclusively aminopyridopyridazine13. The pyridopyridazinones10b,11b, and12b were alkylated with alkyl iodides.
Databáze:	OpenAIRE
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