ChemInform Abstract: A New, Stereoselective, Ring-Forming Reaction of 1,2-Ethanedithiol with N-Acylated Indoles

Autor:	Gennaro Pescitelli, Andreas Eleutheriades, Lorenzo Di Bari, Andrew Tsotinis
Rok vydání:	2008
Předmět:	Indole test chemistry.chemical_compound Annulation Chemistry Product (mathematics) Stereoselectivity 1 2-Ethanedithiol General Medicine Ring (chemistry) Medicinal chemistry
Zdroj:	ChemInform. 39
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200812180
Popis:	While attempting to prepare 2,5-dithiacyclopentyl derivatives from N-acyl 5-fluoroindole by reaction with 1,2-ethanedithiol we discovered that, instead of the expected product, annelation occurred to give a tricyclic compound containing a 3,6-dithiaazepine ring. This reaction is stereoselective and was found to be general for N-acylindoles, not being affected by substituents on the indole ring.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::439a92e1c6c2896ad2eabc5c6e412e23 https://doi.org/10.1002/chin.200812180 Zobrazit plný text záznamu Plný text