Double-exposure method for speckle-tracking x-ray phase-contrast microtomography
Autor: | Yu Fx, Tiqiao Xiao, Guohao Du, Feixiang Wang, Ke Li, Xiaolu Ju, Biao Deng, Haipeng Zhang, Honglan Xie, Mingwei Xu |
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Rok vydání: | 2021 |
Předmět: |
010302 applied physics
Materials science business.industry Phase (waves) General Physics and Astronomy Ranging 02 engineering and technology Edge enhancement 021001 nanoscience & nanotechnology Microstructure Tracking (particle physics) 01 natural sciences Imaging phantom Speckle pattern Optics 0103 physical sciences 0210 nano-technology Phase retrieval business |
Zdroj: | Journal of Applied Physics. 129:073101 |
ISSN: | 1089-7550 0021-8979 |
DOI: | 10.1063/5.0043053 |
Popis: | X-ray phase-contrast microtomography based on speckle tracking is an attractive method for non-destructive three-dimensional imaging owing to its simple setup and ability to yield absorption, refractive, and scattering images simultaneously. However, the edge-enhancement effect usually results in image artifacts or inaccurate phase retrieval, limiting the extensive application of this method in biomedical research and for low-Z materials. In this paper, a double-exposure method is introduced to solve this problem efficiently and accurately. Pure phase samples with various microstructures and densities and a biological sample with a distinct edge-enhancement effect were used to verify the effectiveness of the developed method. In an experiment performed using a polymer phantom with an evenly distributed density, 17 irregularly shaped particles with diameters ranging from 15 to 25 μm were successfully reconstructed with the effective elimination of the edge-enhancement effect. The results obtained for a sample composed of different polymer materials demonstrated that, in contrast with the traditional speckle-tracking method, the present method is able to discriminate materials with similar x-ray attenuations. Finally, experiments were performed using a dehydrated fish, which entail typical edge enhancement and a complex microstructure; notably, it was verified that the fine structure of the fish, including its fins and intestines, was reconstructed completely using the proposed method, whereas the standard speckle-tracking method was ineffective. In conclusion, the developed double-exposure method can serve as an efficient and accurate technique for the x-ray phase-contrast microtomography of samples comprising low-Z materials and complicated microstructures. |
Databáze: | OpenAIRE |
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