| Autor: |
Somi Lee, J. H. Na, Hyejin Jeong, Jung-Sick Lee, Chang-Young Jeong, Seon-Jae Kim, K.Y. Yoo, S.T. Jeong |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Acta Anaesthesiologica Scandinavica. 56:770-776 |
| ISSN: |
0001-5172 |
| DOI: |
10.1111/j.1399-6576.2011.02640.x |
| Popis: |
Background Dose requirements of thiopental depend on patient characteristics and infusion rate. We determined thiopental dose requirements for induction of anaesthesia, and the effects of remifentanil on cardiovascular and bispectral index (BIS) responses to tracheal intubation in spinal cord-injured (SCI) patients undergoing general anaesthesia. Methods Twenty patients with traumatic complete SCI undergoing elective surgery were enrolled. Twenty patients without SCI served as control. Anaesthesia was induced with thiopental, followed by remifentanil 1 μg/kg and rocuronium 0.8 mg/kg, and maintained with 2% sevoflurane and 50% nitrous oxide in oxygen after tracheal intubation. Thiopental was administered at a rate of 50 mg/15 s until abolition of the eyelash reflex. Thiopental doses, BIS values, systolic arterial blood pressure (SAP), heart rate (HR) and plasma catecholamine concentrations were measured. Results Total thiopental dose required to abolish the eyelash reflex based on total body weight (BW) (5.26 ± 0.87 vs. 3.91 ± 1.07 mg/kg, P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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