Clinical Significance of Increased Serum Levels of Troponin I in Patients from the Emergency Department of a County Hospital
| Autor: | Ioana Chirila, Andreea Cotut, Razvan Olimpiu Mada, Diana Larisa Mocan-Hognogi, Alina Buzuriu, Luminita Animarie Vida-Simiti, Adriana Elena Bulboacă, Cerasela Mihaela Goidescu, Adina Maria David, Paul-Mihai Boarescu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Process equipment Materials Science (miscellaneous) Process Chemistry and Technology General Engineering macromolecular substances General Chemistry General Medicine Emergency department musculoskeletal system General Biochemistry Genetics and Molecular Biology Troponin I Emergency medicine cardiovascular system Materials Chemistry medicine Clinical significance In patient cardiovascular diseases General Pharmacology Toxicology and Pharmaceutics |
| Zdroj: | Revista de Chimie. 71:68-73 |
| ISSN: | 2668-8212 0034-7752 |
| DOI: | 10.37358/rc.20.2.7894 |
| Popis: | Elevated cardiac troponin I (cTnI) levels are diagnostic for myocardial injury. Moreover, they are essential for risk stratification in patients with acute cardiac ischemia and heart failure. However, their usefulness is not limited to the previous clinical conditions. The aim of this study was to evaluate the clinical significance of cTnI levels in the emergency department.In 324 patients, out of the 4147 referred to the emergency department, serum levels of cTnI were evaluated and represented the study population. Subjects were divided into 2 groups: Group 1 (66 patients) with cTnI ≥ 0.04 ng/mL and Group 2 (258 patients) with cTnI level [ 0.04 ng/mL. The clinical characteristics, laboratory data, ECG findings, echocardiographic abnormalities and discharge diagnosis were compared between the two groups. Patients with cTnI ≥0.04 ng/mL had more often a history of ischemic heart disease, lower levels of oxygen saturation, higher levels of blood glucose, increased white blood cells count, higher heart rate and deeper ST-segment depressions on ECG. The most common discharge diagnosis was heart failure. Although an elevated level of cTnI is highly suggestive for myocardial injury, it should always be interpretated in the clinical context. Heart failure is an important diagnosis in patients with elevated cTnI levels. |
| Databáze: | OpenAIRE |
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