Association of environmental cadmium exposure and periodontal disease

Autor: Amitha Ramesh, Anju Mary John, Biju Thomas, Rahul Bhandary
Rok vydání: 2013
Předmět:
Zdroj: International Journal of Oral Health Sciences. 3:10
ISSN: 2231-6027
DOI: 10.4103/2231-6027.122088
Popis: Background and Aims: Cadmium adversely affects bone remodeling and is therefore possible that environmental cadmium exposure may be a risk factor for periodontal disease-related bone loss. Aim of the present study was to assess the association between environmental cadmium exposure and periodontal disease. Settings and Design: The study was conducted in the Department of Periodontics, in our institution, Mangalore and sample size consisted of 100 patients (two groups of 50 patients each). Materials and Methods: Gingival Index, periodontal probing depth and clinical attachment loss was estimated to ascertain the gingival and periodontal status of subjects. Urine samples were collected from the subjects and biochemical analysis was done to estimate urine cadmium levels. Statistical Analysis: Results obtained were then statistically analyzed using Mann-Whitney U-test and correlation was done using Karl Pearson's correlation. Results: There was an increased concentration of urinary cadmium in periodontitis patients when compared with the healthy controls and there was a positive correlation between age and cadmium concentrations. Conclusion: Although information on the oral health effects of cadmium remains limited, the results of this study suggests that cadmium exposure may be an important risk factor for periodontal disease in adults.
Databáze: OpenAIRE