Fractionated Stereotactic Radiation Therapy (FSRT) for Brain Metastases From Non-small Lung Carcinoma: Relationship Between the Number of Metastases and Intracranial Relapse
| Autor: | Tomohiko Matsuyama, K. Kogo, Natsuo Oya |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Oncology
Cancer Research medicine.medical_specialty Pediatrics Radiation Lung business.industry medicine.medical_treatment Stereotactic radiation therapy medicine.disease Anticonvulsant medicine.anatomical_structure Internal medicine Toxicity Carcinoma Medicine Radiology Nuclear Medicine and imaging Risks and benefits business |
| Zdroj: | International Journal of Radiation Oncology*Biology*Physics. 84:S293 |
| ISSN: | 0360-3016 |
| DOI: | 10.1016/j.ijrobp.2012.07.764 |
| Popis: | anticonvulsants more frequently had higher estimations of the maximum two-week risk of seizures (Kruskal-Wallis p < 0.001). For example, respondents who used anticonvulsants ‘always’ or ‘usually’ had a median estimate of the maximum seizure risk of 10%, while those who responded ‘never’ estimated the risk to be 3%. Conclusion: There is wide variability in the use of prophylactic steroids and anticonvulsant medications for patients undergoing SRS. Further investigation of the actual seizure risk after SRS and the risks and benefits of prophylactic medications is warranted, and may lead to more patientcentered, rational prescribing practices, to minimize toxicity and cost and maximize clinical utility. Author Disclosure: N.D. Arvold: None. N.E. Pinnell: None. A. Mahadevan: None. S. Connelly: None. R. Silverman: None. S.E. Weiss: None. P.J. Kelly: None. B.M. Alexander: None. |
| Databáze: | OpenAIRE |
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