Health economic evaluation of peritoneal dialysis based on cost-effectiveness in Japan: a preliminary study

Autor: Tomoyuki Takura, Hironori Ishida, Makoto Hiramatsu, Masaaki Nakayama, Hidetomo Nakamoto, Jun Minakuchi, Susumu Takahashi, Takahiro Kuragano, Hideki Kawanishi
Rok vydání: 2019
Předmět:
Zdroj: ClinicoEconomics and Outcomes Research. 11:579-590
ISSN: 1178-6981
DOI: 10.2147/ceor.s212911
Popis: Background In Japan, the medical expenditures associated with dialysis have garnered considerable interest; however, a cost-effectiveness evaluation of peritoneal dialysis (PD) is yet to be evaluated. In particular, the health economics of the "PD first" concept, which can be advantageous for clinical practice and healthcare systems, must be evaluated. Methods This multicenter study investigated the cost-effectiveness of PD. The major effectiveness indicator was quality-adjusted life year (QALY), with a preference-based utility value based on renal function, and the cost indicator was the amount billed for a medical service at each medical institution for qualifying illnesses. In comparison with hemodialysis (HD), a baseline analysis of PD therapy was conducted using a cost-utility analysis (CUA). Continuous ambulatory PD (CAPD) and automated PD (APD) were compared based on the incremental cost-utility ratio (ICUR) and propensity score (PS) with a limited number of cases. Results The mean duration since the start of PD was 35.0±14.4 months. The overall CUA for PD (179 patients) was USD 55,019/QALY, which was more cost effective (USD/monthly utility) compared with that for HD for 12-24 months (4,367 vs. 4,852; p
Databáze: OpenAIRE