| Autor: |
Nkhaili A, Semlali R, Aouroud M, Chakor F, Errami AA, Oubaha S, Samlani Z, Krati K |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Japanese Journal of Gastroenterology and Hepatology. |
| DOI: |
10.47829/jjgh.2021.8102 |
| Popis: |
Primary Biliary Cholangitis (PBC) isa cholestatic disease of autoimmune origin characterized by the destruction of small to medium size intrahepatic bile ducts due to lymphocytic infiltration. The diagnosis is made by the presence of Anti-Mitochondrial Antibodies (AMAs) specific for the disease. PBC typically affects middle-aged women and is often associated with other autoimmune pathologies which are in decreasing order of frequency: Sjogren's syndrome, autoimmune dysthyroidism, scleroderma, rheumatoid arthritis, lupus and celiac diseasewhich are also more common in women. Few clinical studies evaluate the presentation of PBC in men with concomitant type 1 diabetes due to its low incidence compared to the prevalence of PBC in women.This case report presents that of a male patient with type 1 diabetes, admitted for cholestatic jaundice with pruritus, and in whom the diagnosis of PBC was only made late in the cirrhosis stage |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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