Issues in diagnosis of small B cell lymphoid neoplasms involving the bone marrow and peripheral blood. Report on the Bone Marrow Workshop of the XVIIth meeting of the European Association for Haematopathology and the Society for Hematopathology
| Autor: | Anna Porwit, Mukerrem Safali, Falko Fend, Marcus Kremer, Jon van der Walt, Attilio Orazi |
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| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Histology Hematology business.industry Cytogenetics Lymphoproliferative disorders General Medicine medicine.disease Pathology and Forensic Medicine Lymphoma 03 medical and health sciences 0302 clinical medicine Immunophenotyping medicine.anatomical_structure 030220 oncology & carcinogenesis Internal medicine Immunology medicine Bone marrow Hematopathology business B cell 030215 immunology |
| Zdroj: | Histopathology. 69:349-373 |
| ISSN: | 0309-0167 |
| DOI: | 10.1111/his.12999 |
| Popis: | Small B cell lymphoid neoplasms are the most common lymphoproliferative disorders involving peripheral blood (PB) and bone marrow (BM). The Bone Marrow Workshop (BMW) organized by the European Bone Marrow Working Group (EBMWG) of the European Association for Haematopathology (EAHP) during the XVIIth EAHP Meeting in Istanbul, October 2014, was dedicated to discussion of cases illustrating how the recent advances in immunophenotyping, molecular techniques and cytogenetics provide better understanding and classification of these entities. Submitted cases were grouped into following categories: (i) cases illustrating diagnostic difficulties in chronic lymphocytic leukaemia (CLL); (ii) cases of BM manifestations of small B cell lymphoid neoplasms other than CLL; (iii) transformation of small B cell lymphoid neoplasms in the BM; and (iv) multiclonality and composite lymphomas in the BM. This report summarizes presented cases and conclusions of the BMW and provides practical recommendations for classification of the BM manifestations of small B cell lymphoid neoplasms based on the current state of knowledge. |
| Databáze: | OpenAIRE |
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