Electron Microscopic Detection of Virus Particles in the Rhino Mouse**Churchwell MA, Belew PW, Rosenberg EW, Pitcock JA, Brown PS, Gupta RC: EM Detection of Virus particles in the Rhino Mouse. Clin Res 31(5):920A, 1983. Churchwell MA, Belew PW, Bale G, Pitcock JA, Brown PS, Gupta RC: Immunoglobulins and Viral Particles in the Skin of the Rhino Mouse. Clin Res 32(2): 576A, 1984

Autor:	P.S. Brown, M.A. Churchwell, E.W. Rosenberg, Patricia W. Noah, G. F. Bale, R.C. Gupta, J.A. Pitcock
Rok vydání:	1986
Předmět:	Lupus erythematosus biology Immunoperoxidase viruses General Medicine biology.organism_classification medicine.disease Virology Virus law.invention medicine.anatomical_structure Dermis Antigen law Murine leukemia virus medicine biology.protein Antibody Electron microscope
Zdroj:	The American Journal of the Medical Sciences. 291:314-320
ISSN:	0002-9629
DOI:	10.1097/00000441-198605000-00005
Popis:	The rhino mouse, an experimental model for systemic lupus erythematosus, was found to have murine leukemia virus particles present in the skin. Immunoperoxidase studies with anti-type C virus antibody indicated viral antigen presence in the sebaceous cells and surrounding follicular cysts of the dermis. Electron microscope studies show virus particles, both type C extracellularly and type A intracellularly, around follicular cysts. Virus particle was labeled with specific ferritin-conjugated antitype C virus antibody.
Databáze:	OpenAIRE
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