219: Mechanically Ventilated Patients With SARS-CoV-2 Infection: A Single-Institution Analysis

Autor: Javaria Syeda, Binu Kuriakose, Gashaw Dadi, Muyide Satiregun, Mohammad Hamad, Nida Hameedi, Farrah Anwar, Sairah Khadija, Maciej Walczyszyn, David Wisa, Muhammad Osama, Lubna Ali
Rok vydání: 2020
Předmět:
Zdroj: Critical Care Medicine. 49:95-95
ISSN: 0090-3493
DOI: 10.1097/01.ccm.0000726764.79786.c3
Popis: INTRODUCTION: To identify characteristics and comorbidities as correlative factors in risk assessment for disease severity in mechanically ventilated patients infected with SARS-CoV-2 at a single hospital institution and the uses of these factors and outcomes to determine correlative risk for mortality METHODS: A retrospective cohort study of patients who were admitted at Flushing Hospital Medical Center with confirmed infection of SARS-CoV-2 requiring invasive mechanical ventilation, admitted between March 1, 2020 and May 8, 2020 and their outcomes were followed through May 31, 2020 Patient data was reviewed retrospectively through accessing electronic medical records (EPIC) and descriptive statistics were used to analyze the data RESULTS: A total of 192 patients were included [Mean age ± SD (66 43±13 67)] Among these patients 67 2% were male and 32 8% were female Various co-morbidities and lab parameters were assessed as a risk for mortality and outcomes The number of expired patients was 149 (77 6%), 35 (18 2%) remained alive and the status of 8 (4 2%) patients was missing as they were transferred to another facility These patients had a mean (SD) BMI of 28 34 (6 5) Commonly presenting symptoms included shortness of breath (62 5%), cough (50%) and fever (47 9%) During the course of hospitalization 27 (14 1%) patients were transferred to another facility for further care due to limited availability of beds Median duration of intubation was 7 days (minimum 3, maximum 52) Among all the patients who expired, 52 2% had severe acute respiratory distress syndrome (ARDS), 30 9% had moderate ARDS and 11% had mild ARDS Most common complications were acute kidney injury requiring hemodialysis (13%) and arrhythmia (12 5%) Median number of days of hospitalization before expiration was 10 days (minimum 0, maximum 61) CONCLUSIONS: This study provides characteristics and co-morbidities of mechanically ventilated patients and their outcomes including overall mortality Hypertension, diabetes and presence of more than one comorbidity was associated with significant increase in mortality Administration of hydroxychloroquine, azithromycin and methylprednisolone was not found to have a significant effect on outcome and mortality
Databáze: OpenAIRE