Core/shell structured iron/iron-oxide nanoparticles as excellent MRI contrast enhancement agents
| Autor: | Hui Mao, Costas G. Hadjipanayis, Hongwei Chen, Vasilis Tzitzios, Wanfeng Li, George C. Hadjipanayis, Hafsa Khurshid, Revaz Machaidze |
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| Rok vydání: | 2013 |
| Předmět: |
Aqueous solution
Materials science Ethylene oxide Nanoparticle Nanotechnology engineering.material Condensed Matter Physics Electronic Optical and Magnetic Materials Metal Solvent chemistry.chemical_compound Chemical engineering Coating chemistry visual_art engineering visual_art.visual_art_medium Copolymer Iron oxide nanoparticles |
| Zdroj: | Journal of Magnetism and Magnetic Materials. 331:17-20 |
| ISSN: | 0304-8853 |
| DOI: | 10.1016/j.jmmm.2012.10.049 |
| Popis: | We report the use of metallic iron-based nanoparticles for magnetic resonance imaging (MRI) applications. Core/shell structured iron-based nanoparticles prepared by thermally decomposing organo-metallic compounds of iron at high temperature in the presence of hydrophobic surfactants were coated and stabilized in the aqueous solvent using the newly developed polysiloxane PEO–b–PγMPS (poly(ethylene oxide)–block–poly (γ methacryloxypropyl trimethyl oxysilane)) diblock copolymers. Particles are well suspended in water and retain their core–shell morphology after coating with the copolymer. In comparison to the conventionally used iron-oxide nanoparticles, core/shell structured iron/iron-oxide nanoparticles offer a much stronger T 2 shortening effect than that of iron-oxide with the same core size due to their better magnetic properties. |
| Databáze: | OpenAIRE |
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