Is osteoporosis risk in anorexia nervosa underestimated? A case report series

Autor:	Simone Belli, Luca Di Paolo, B. Cotugno, Mauro Mauri, Claudio Cargioli, Samanta Augusto, B. Pacciardi
Rok vydání:	2013
Předmět:	Bone mineral medicine.medical_specialty education.field_of_study Pediatrics business.industry Osteoporosis Population Bone fracture medicine.disease Anorexia nervosa Lumbar Weight loss medicine Physical therapy Amenorrhea medicine.symptom business education
Zdroj:	Open Journal of Internal Medicine. :115-118
ISSN:	2162-5980 2162-5972
DOI:	10.4236/ojim.2013.34025
Popis:	Introduction: Anorexia nervosa (AN) is a mental disorder whose features are deliberate weight loss, disordered body image, and intrusive overvalued fears of gaining weight. Long-term consequences of AN include endocrine dysfunctions leading to secondary amenorrhea, bone loss and/or osteoporosis with an increased risk of bone fracture. Therefore young women with AN may develop a risk for bone fractures comparable to that of postmenopausal women. Methods: In this case report series Bone Mineral Density (BMD) was examined by Dual energy X-ray Absorptiometry (DXA) in 19 hospitalized patients with diagnosis of AN and prolonged amenorrhea. Results: All patients showed a lumbar/femoral bone loss or osteoporosis, with an increased fracture risk comparable to that of postmenopausal women. Conclusions: Our observation suggests that DXA evaluation of anorexic patients with prolonged amenorrhea would be helpful to prevent fracture risk in this population of patients. However, although DXA is almost routinely recommended in women over 65, it is not in young AN patients with prolonged amenorrhea.
Databáze:	OpenAIRE
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