Synthesis of bridged 1,4-diazepane derivatives via Schmidt reactions

Autor: Pavel K. Mykhailiuk, Dmitriy M. Volochnyuk, Oleksandr O. Grygorenko, Andrey A. Tolmachev, Aleksandr V. Denisenko, Andrey P. Mityuk, Oleksandr P. Dacenko
Rok vydání: 2010
Předmět:
Zdroj: Tetrahedron Letters. 51:1790-1792
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2010.01.121
Popis: A series of bridged 1,4-diazepanes (i.e., diazabicyclo[n.3.2]alkanes, n = 3–5) selectively protected at one of the nitrogen atoms was prepared, for possible application in drug design, via Schmidt rearrangement of the corresponding ketones.
Databáze: OpenAIRE