Characterization of an Electrospray Ion Source as a Controlled-Current Electrolytic Cell
| Autor: | G. J. Van Berkel, Feimeng Zhou |
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| Rok vydání: | 1995 |
| Předmět: | |
| Zdroj: | Analytical Chemistry. 67:2916-2923 |
| ISSN: | 1520-6882 0003-2700 |
| DOI: | 10.1021/ac00113a028 |
| Popis: | An electrospray (ES) ion source is described as a constant or controlled-current device for which the magnitude of the ES current is controlled by the rate of charged droplet production. Thus, the nature of the electrolytic process that occurs in the metal ES capillary to charge balance the loss of one ion polarity in the charged droplets is shown to be analogous to that of a controlled-current electrolytic (CCE) cell and controlled-current electrolysis carried out in a flow cell. Experimental confirmation of the ES ion source as a CCE cell is made through experiments employing a novel ES ion source in which the effluent from the ES capillary enters the detection cell of a UV/visible diode array spectrophotometer prior to the spraying process. This ES setup allowed for the first time the detection of the products of the redox reactions in the ES capillary, while they were still in solution, thereby avoiding experimental complications imposed by the spraying process or by the subsequent mass analysis of the gas-phase ions that might complicate data interpretation. The analytical implications of the operation of the ES ion source as a CCE cell for neutral compound ionization and detection in ES-MS are briefly discussed.more » 31 refs., 7 figs.« less |
| Databáze: | OpenAIRE |
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