Sonographic and Doppler characteristics of the corpus luteum: can they predict pregnancy outcome?

Autor: Carol B. Benson, Mary C. Frates, Sara M. Durfee, Douglas L. Brown, Peter M. Doubilet, Faye C. Laing, Joseph A. Hill, Donald N. Di Salvo
Rok vydání: 2001
Předmět:
Zdroj: Journal of Ultrasound in Medicine. 20:821-827
ISSN: 0278-4297
DOI: 10.7863/jum.2001.20.8.821
Popis: Objective To determine whether there is a relationship between gray scale or Doppler characteristics of the corpus luteum and first-trimester pregnancy outcome. Methods We conducted a prospective study of patients with spontaneous singleton pregnancies between 5 and 8 weeks' gestation. The corpus luteum size, sonographic appearance, resistive index, and peak systolic velocity were measured on transvaginal sonography. Maternal use of exogeneous progesterone was recorded. Only patients with known first-trimester outcome were included. Results There were 201 study patients. The corpus luteum could be visualized in 197 (98%) and had a mean +/- SD size of 1.9 +/- 0.6 cm, a mean resistive index of 0.50 +/- 0.08, and a peak systolic velocity of 20.5 +/- 11.2 cm/s. There were 151 first-trimester survivors (75.1 %) and 50 spontaneous losses (24.9%). In a comparison of the survivors and losses, there was no significant difference in mean corpus luteum size (1.9 versus 1.7 cm; P = .10, t test), mean resistive index (0.50 versus 0.50; P = .71, t test), peak systolic velocity (21 versus 19 cm/s; P = .29, t test), or sonographic appearance (P = .78, chi2 test). The lack of association between corpus luteum characteristics and outcome persisted when cases were stratified by progesterone use and the presence or absence of a heartbeat on the study sonogram. Conclusion There is no apparent relationship between the characteristics of the corpus luteum and first-trimester pregnancy outcome.
Databáze: OpenAIRE