Prevalence and Predictors of Distress in Young Women with Newly Diagnosed Early Stage Breast Cancer

Autor: Mara S. Meyer, Shari Gelber, Rulla M. Tamimi, EP Winer, Erica L. Mayer, AH Partridge, Kathryn J. Ruddy, S Come, Lidia Schapira
Rok vydání: 2009
Předmět:
Zdroj: Cancer Research. 69:1067-1067
ISSN: 1538-7445
0008-5472
DOI: 10.1158/0008-5472.sabcs-09-1067
Popis: Background: Previous research suggests that young women are at high risk for psychological distress after a breast cancer diagnosis. We sought to identify factors associated with overall distress, anxiety, and depression in this vulnerable population.Materials and Methods: We have surveyed women age ≤40 with recently diagnosed stage I-III breast cancer in an ongoing prospective multi-center cohort study started in late 2006. The baseline survey includes the Hospital Anxiety and Depression Scale (HADS) as well as sociodemographic and medical history items. Medical record and central pathology review were also performed. Women with HADS scores >14 were considered distressed, and those with scores >10 on the anxiety or depression subscales were considered anxious or depressed, respectively. We conducted multivariate logistic regression modeling to determine predictors of anxiety, depression, and overall distress.Results: The first 258 eligible women who completed the baseline survey are included in this analysis. Median age at diagnosis was 37 years. Seventy-six percent were married, 90% white, 83% college educated, 66% had children, 99% were medically insured, and 60% were employed full time prior to diagnosis. Fifty-two percent of women reported their finances as comfortable. Forty-eight percent reported a household income over $100,000 per year, and only 15% reported an income less than $50,000. Comfortable finances and higher reported income were strongly correlated (Spearman's correlation coefficient = 0.51, p Citation Information: Cancer Res 2009;69(24 Suppl):Abstract nr 1067.
Databáze: OpenAIRE