Laryngeal cancer in Finland: A 5-year follow-up study of 366 patients
| Autor: | Petri Koivunen, Mervi Närkiö Md, Aaro Haapaniemi, Reidar Grénman, Leena-Maija Aaltonen, Timo Atula, Jussi Laranne, Paula Lindholm, Antti Mäkitie, Kauko Saarilahti, Ilpo Kinnunen |
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| Rok vydání: | 2015 |
| Předmět: |
Larynx
medicine.medical_specialty 5 year follow up business.industry medicine.medical_treatment Cancer medicine.disease University hospital Surgery Radiation therapy stomatognathic diseases 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Otorhinolaryngology 030220 oncology & carcinogenesis medicine Carcinoma Patient group 030223 otorhinolaryngology business Chemoradiotherapy |
| Zdroj: | Head & Neck. 38:36-43 |
| ISSN: | 1043-3074 |
| DOI: | 10.1002/hed.23834 |
| Popis: | Background The purpose of this study was to acquire nationwide data on the management and outcome of laryngeal squamous cell carcinoma (SCC) in Finnish university hospitals over a 5-year posttreatment follow-up. Methods All records of patients diagnosed and treated for primary laryngeal SCC during 2001 to 2005 were reviewed. Results Three hundred sixty-six patients with laryngeal cancer were identified, 360 of whom had laryngeal SCC. Three hundred forty-two patients with laryngeal SCC (95%) were treated with curative intent. Five-year disease-specific survival (DSS) for T1a, T1b, T2, T3, and T4 glottic SCC was 100%, 95%, 78%, 79%, and 53%, respectively. The corresponding figures for T1 to T4 supraglottic SCC were 68%, 54%, 72%, and 59%. Conclusion Results of this nationwide study give a general overview of the outcome of unselected patients treated with unified guidelines. Patients with T2 tumors, usually treated with radiotherapy (RT), had a worse prognosis than expected. This patient group warrants further investigation and possibly treatment intensification. © 2015 Wiley Periodicals, Inc. Head Neck, 2015 |
| Databáze: | OpenAIRE |
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