Fabrication of hydrophobic surfaces on Titanium using Micro-EDM exhibiting antibacterial properties
Autor: | Arjita Das, Shikha Ambastha, Nivedita Priyadarshni, Sudip Samanta, null Nagahanumaiah |
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Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture. 236:1093-1101 |
ISSN: | 2041-2975 0954-4054 |
Popis: | Microbial contamination on medical assistive devices has been the major challenge for biomedical industries. The present work is focused on producing patterned surfaces on commercially pure Titanium (cp-Ti) using Micro-Electrical Discharge Machining (Micro-EDM) technique, and the feasibility of patterned surface in restricting bacterial growth. Geometrical patterning in form of micro-holes have been produced on cp-Ti biomaterials with Micro-EDM in two forms, one with 20 µm inter-distance forming a dense pattern and the other with 60 µm inter-distance forming a sparse pattern. The patterned surface establishes the degree of hydrophobicity as 130° and 106° for densely patterned and sparsely patterned surfaces respectively. Further, the effect of bacterial adhesion over the textured cp-Ti surfaces are challenged with model bacteria gram negative Escherichia coli (e.coli) in Luria broth (LB) agar media. The Colony Forming Unit (CFU) count obtained for densely patterned surface compared with that of non-patterned surface reflects 90% reduced bacterial growth. The instances of pattern formation and bacterial growth have been observed with Scanning Electron Microscopy. The enhanced material properties with micro-patterning that combat microbial activities on the biomaterial surface proves its efficacy in adoption for biomedical applications, with significant reduction in bacterial contamination on medical devices or implants, leading toward reduced healthcare risks and issues related to bacterial infections on the biomaterials. |
Databáze: | OpenAIRE |
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