Features of the immune status in patients with bullous lesions of the oral mucosa with complex treatment using photodynamic therapy
| Autor: | O F Rabinovich, I M Rabinovich, E.S. Abramova, K.V. Umarova |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Pemphigoid
medicine.medical_specialty integumentary system biology business.industry medicine.medical_treatment Pemphigus vulgaris Clinical course Photodynamic therapy medicine.disease Dermatology Proinflammatory cytokine Bullous lesions stomatognathic diseases medicine.anatomical_structure medicine biology.protein Oral mucosa Antibody skin and connective tissue diseases business |
| Zdroj: | Clinical Dentistry. :32-35 |
| ISSN: | 1811-153X |
| DOI: | 10.37988/1811-153x_2019_4_32 |
| Popis: | In this article the indicators of innate immunity in oral fluid were studied in 75 patients with bullous lesions of the oral mucosa (pemphigus vulgaris (18), pemphigoid bullosa (25) and bullous form of lichen ruber planus (32)) before and after complex treatment with the inclusion of photodynamic therapy. Indicators of the level of proinflammatory cytokines IL-1β, IL-2, IL-6, TNF-α and immunoglobulins A, M, G were determined. 10 people who turned to a dentist for the treatment of caries and its complications served as control; somatic pathology and signs indicating the presence of autoimmune diseases of the oral mucosa, they were not revealed. This study established the relationship between the level of proinflammatory cytokines and immunoglobulins with the severity of the clinical course of bullous lesions, which causes the use of photodynamic therapy in the complex treatment of these diseases of the oral mucosa. |
| Databáze: | OpenAIRE |
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