New postmortem diagnostic biomarker for myocardial infarction: ischemia modified albumin
Autor: | A. Tuba Kocaman, Muzaffer Yildirim, Safa Çelik, Saadet Alpdoğtaş, H. Büşra Konak, Mustafa Çeltek, Ahmet Hazini, Fatih Yağmur, Mustafa Cemek |
---|---|
Rok vydání: | 2017 |
Předmět: |
Postmortem Diagnosis
Asphyxia medicine.medical_specialty Forensic pathology business.industry 010401 analytical chemistry Autopsy medicine.disease 01 natural sciences 0104 chemical sciences Pathology and Forensic Medicine Surgery 03 medical and health sciences 0302 clinical medicine Blunt trauma Internal medicine medicine Cardiology 030216 legal & forensic medicine Myocardial infarction medicine.symptom business Pathological Cause of death |
Zdroj: | Australian Journal of Forensic Sciences. 51:191-200 |
ISSN: | 1834-562X 0045-0618 |
Popis: | We investigated the change of IMA levels as biochemical markers, especially in the postmortem diagnosis of early MI. Also, histological investigation has been performed in cases of cardiac deaths and in non-cardiac cases. To the best of our knowledge, this is the first study to investigate the levels of IMA in the postmortem diagnosis of early MI. A series of medicolegal autopsy cases (n=139; 6–24 h postmortem, with a median of 16 h) were examined at our institute. The cases comprised 112 males and 27 females, between 16 and 89 years of age. Subjects were divided into six groups depending upon their final cause of death according to medical data, autopsy reports, biochemical and histological findings. The groups were as follows: cardiovascular disease, blunt trauma, asphyxia, pathological cerebral hemorrhage, bleeding due to a sharp object and gunshot injuries, and poisoning. IMA levels in the cardiovascular disease group were found to be significantly higher than the blunt trauma, asphyxia, patho... |
Databáze: | OpenAIRE |
Externí odkaz: |