Laser-assisted uvulopalatoplasty (LAUP) complications and side effects: a systematic review
Autor: | Uneeb Qureshi, Macario Camacho, Jeffrey D. Wischhusen |
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Rok vydání: | 2019 |
Předmět: |
medicine.medical_specialty
education.field_of_study business.industry Incidence (epidemiology) medicine.medical_treatment Population Apnea medicine.disease Uvulopalatoplasty Surgery Dysgeusia Obstructive sleep apnea 03 medical and health sciences Behavioral Neuroscience Stenosis 0302 clinical medicine 030228 respiratory system Relative risk medicine medicine.symptom education business 030217 neurology & neurosurgery Applied Psychology |
Zdroj: | Nature and Science of Sleep. 11:59-67 |
ISSN: | 1179-1608 |
Popis: | Objective: Laser-assisted uvulopalatoplasty (LAUP) has been used as a treatment option for snoring and obstructive sleep apnea for almost three decades. It has been previously reported that some patient's sleep-disordered breathing worsened following surgery. The aim of this paper is to further elucidate the specific complications of LAUP. Data sources: A systematic search of the electronic databases MEDLINE/PubMed, Google Scholar, and Embase. Review methods: The PRISMA statement was followed. Databases were searched from inception through September 2, 2018. The following search was applied to MEDLINE/PubMed ((laser AND uvul*) OR (LAUP) OR (LAVP) OR (laser AND (apnea OR apnoea OR sleep))). Results: Forty-two studies with a mean follow-up of 16.1 months reported complications on 3,093 total patients who underwent LAUP. The percentages and associated complications of LAUP are as follows: bleeding (2.6%), candidiasis (0.3%), dryness (7.2%), dysgeusia (0.3%), dysosmia (0.2%), globus sensation (8.2%), surgical site infection (1.3%), velopharyngeal (VP) insufficiency (3.9%), and VP stenosis (1.6%). The mean duration of patient-reported pain in studies that reported pain was 11.65 days. Only globus and VP insufficiency had a significant incidence compared with either the general population or the post-oropharyngeal surgery population with relative risks of 1.48 and 2.25, respectively. Overall, there were approximately 26 complications per 100 patients who underwent LAUP. Conclusion: LAUP is associated with a statistically significant rate of VP insufficiency and globus sensation; however, studies lack details of surgical approaches, suggesting that in a population identified as good candidates, a tissue-sparing approach may result in fewer complications. |
Databáze: | OpenAIRE |
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