Bronchopulmonary dysplasia associated pulmonary hypertension: Making the best use of bedside echocardiography
| Autor: | Arvind Sehgal, Gopagondanahalli Krishna Revanna, Ansar Kunjunju |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Pediatrics
medicine.medical_specialty business.industry Incidence (epidemiology) Gestational age 030204 cardiovascular system & hematology medicine.disease Pulmonary hypertension Respiratory support 03 medical and health sciences 0302 clinical medicine Bronchopulmonary dysplasia 030225 pediatrics mental disorders Pediatrics Perinatology and Child Health Cohort medicine Clinical significance Respiratory system Cardiology and Cardiovascular Medicine business |
| Zdroj: | Progress in Pediatric Cardiology. 46:39-43 |
| ISSN: | 1058-9813 |
| Popis: | Pulmonary hypertension (PH) complicating bronchopulmonary dysplasia (BPD) is known though echocardiographic (ECHO) criteria and clinical relevance are unclear. An audit of infants ≤ 28 weeks' gestational age (GA) and with ‘severe’ BPD was carried out for the period January 2014 to May 2015. Six objective ECHO markers were decided a priori. During the period, 56 infants with GA and birthweight of 26 ± 1.4 weeks and 796 ± 190 g had ‘severe’ BPD. Twenty (35%) infants had no echocardiogram performed after 34 weeks' corrected GA; the remaining 36 infants had an echocardiogram at 36.7 ± 2 weeks' GA. ECHO parameters indicative of PH were noted in 22 (39.3%) infants in the overall cohort. The most common parameter was tricuspid regurgitation in 13/36 (36%) infants. The GA of infants with and without PH was comparable (25.8 ± 1.6 vs 25.8 ± 1.3 weeks, p = 0.9). The total duration of respiratory support in the BPD with PH group was significantly longer compared to those without (224 ± 130 vs 132 ± 82 days, p = 0.001). Overall, 29 (52%) infants were discharged on oxygen/respiratory support; the odds when PH was present were 2.2 (95% CI 0.8–5.7). This was not statistically significant. BPD associated PH contributes to respiratory sequelae. Objective ECHO criteria may aid ascertaining true incidence. |
| Databáze: | OpenAIRE |
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