Case Reports: Late Seminomatous Relapse of a Mixed Germ Cell Tumor of the Testis on Intensive Surveillance

Autor:	L. Jonathan Zwi, Vernon J. Harvey, Michael R. McCrystal
Rok vydání:	1995
Předmět:	Pathology medicine.medical_specialty Mixed Germ Cell Tumor medicine.diagnostic_test business.industry Urology Physical examination Disease Metastatic Mass medicine.disease Curative treatment medicine Germ cell tumors Orchiectomy Radiology business
Zdroj:	Journal of Urology. 153:1057-1059
ISSN:	1527-3792 0022-5347
DOI:	10.1016/s0022-5347(01)67640-7
Popis:	We report a case of a pure seminomatous relapse in the retroperitoneum 6 years after orchiectomy for an apparent stage I mixed germ cell tumor of the testis. The 4 cm. metastatic mass was not imaged on computerized tomography, tumor markers were negative and confounding symptoms made diagnosis difficult. The propensity for seminomatous tumors to relapse later than nonseminomatous tumors has profound implications for intensive surveillance programs for apparent stage I disease in mixed germ cell tumors. These programs often involve routine computerized tomography only for the first 2 years and rely on physical examination, simple radiology and serum tumor markers thereafter. Such programs may fail to detect pure seminomatous relapse and delay the onset of curative treatment.
Databáze:	OpenAIRE
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