Common laboratory mice are susceptible to infection with SARS-CoV2 beta variant

Autor: Anja Kipar, Sawan Kumar Jha, Kalle Saksela, Ravi Kant, Tomas Strandin, Seppo Meri, Teemu Smura, Kari Alitalo, Tobias L. Freitag, Tarja Sironen, Lauri Kareinen, Olli Vapalahti
Rok vydání: 2021
Předmět:
Popis: Small animal models are of crucial importance for assessing COVID-19 countermeasures. Common laboratory mice would be well-suited for this purpose but are not susceptible to infection with wild-type SARS-CoV-2. Herein we show that the SARS-CoV-2 beta variant attains infectibility to BALB/c mice and causes pulmonary changes consistent with COVID-19.
Databáze: OpenAIRE